Public access to protocols of contemporary cancer randomized clinical trials
نویسندگان
چکیده
منابع مشابه
Promoting public access to clinical trial protocols: challenges and recommendations
BACKGROUND Recognizing the value of promoting public access to clinical trial protocols, Trials pioneered the way for their publication over a decade ago. However, despite major advances in the public accessibility of information about trial methods and results, protocol sharing remains relatively rare. MAIN BODY Protocol sharing facilitates the critical appraisal of clinical trials and helps...
متن کاملOpen access to clinical trials data.
Well-conducted randomizedclinical trials (RCTs) are thegold standard for evaluating the safety and efficacy of medical therapeutics. Yet most often, a single group of individuals who conducted the trial are the only ones who have access to the raw data, conduct the analysis, and publish the study results. This limited access does not typically allow others to replicate the trial findings. Given...
متن کاملBetter access to information about clinical trials.
Access to information about clinical trials is important to researchers, health care professionals, and patients. Many have argued for the establishment of clinical trials registries, citing their substantial benefits. Although some registries do exist, it has been difficult to create comprehensive, easily accessible systems. This paper briefly reviews existing registries, discusses the challen...
متن کاملEvaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملThe impact of insurance on access to cancer clinical trials at a comprehensive cancer center.
PURPOSE Cancer patients at Johns Hopkins undergo insurance clearance to verify coverage for enrollment to interventional clinical trials. We sought to explore the impact of insurance clearance on disparities in access to cancer clinical trials at this urban comprehensive cancer center. EXPERIMENTAL DESIGN We evaluated the frequency of insurance-based denial of access to cancer clinical trials...
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ژورنال
عنوان ژورنال: Trials
سال: 2021
ISSN: 1745-6215
DOI: 10.1186/s13063-021-05382-7